Tkinter: The standard Python library for creating GUI applications. It is simple and easy to use, making it an excellent choice for beginners.
PyQt: A popular Python binding for the Qt library, a robust cross-platform framework for creating GUI applications.
wxPython: A wrapper for the wxWidgets library, a cross-platform GUI toolkit for creating desktop applications.
PyGTK: A set of Python bindings for the GTK library, a popular toolkit for creating GUI applications on Linux and other Unix-like systems.
PySide: A Python binding for the Qt library, similar to PyQt, with a slightly different API.
Kivy: An open-source Python library for creating multi-touch applications, such as games and interactive applications.
Pyforms: A Python library for creating GUI applications using a simple and intuitive API.
PyFLTK: A Python wrapper for the FLTK library, a lightweight, cross-platform GUI toolkit.
PySimpleGUI: A simple yet powerful GUI library for Python that is easy to use and provides many features.
Pygame: A set of Python modules designed for creating games and other multimedia applications. It also includes a simple GUI module for creating menus and other essential UI elements.